Peter, the son of a rich and influential family, dies from a drug overdose. When the autopsy reveals that he did not commit suicide but was poisoned, the three detectives Kalumba, Salamisha and Chokbank start their investigations and are drawn into a maelstrom of intrigue, greed and violence. To find Pete's murderer, they must descend into the world of counterfeit drugs where unscrupulous profiteers exploit the sick and desperate. Counterfeit medicine is sold cheaply and people are unaware of the threat it poses to their health. Several leads take the detectives to a famous doctor, a traditional healer, a pharmacist and all the way to the minister of health. As the investigation progresses, the detectives’ lives are threatened more than once. In the end, they are able to determine the extent of Peter's involvement with this dirty business and why he had to die.